Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificanceDuring tissue repair, mature, specialized cells can revert to a stem cell–like state via cellular programs like paligenosis. We show, in stomach chief cells, that the protein YAP1 is activated in paligenosis and that Serine/Threonine Kinase 38 ...
PNAS published a clinical update in Research Highlights on 30 Mar 2026.
The item focuses on Regulation of STK38 by autophagy governs YAP1 activity during paligenosis.
Review the original article for the full source wording and details.