Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceRNA modifications like 5-methylcytosine (m5C) are emerging as critical regulators of inflammation, but their functional role in kidney diseases remains unknown. We identify NOP2/Sun RNA methyltransferase family member 7 (NSUN7) promotes renal ...
PNAS published a clinical update in Research Highlights on 23 Mar 2026.
The item focuses on The m5C orchestrator NSUN7 drives SPARC/HMGB1 axis–mediated inflammation to exacerbate kidney injury.
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