Proceedings of the National Academy of Sciences, Volume 123, Issue 17, April 2026. SignificanceThis study reveals how cancer cells resist the targeted drug sorafenib.
We found that the protein Aurora-A, known for its role in cell division, can form liquid-like droplets in the cytoplasm under drug stress. These droplets help build ...
PNAS published a clinical update in Research Highlights on 20 Apr 2026. The item focuses on Aurora-A drives sorafenib resistance by scaffolding stress granule assembly via phase separation. Open the detail page to review the full original feed content.