Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificanceOur study reports the generation and characterization of two mouse models in which endogenous SMAD2 and SMAD3 are epitope-tagged, enabling high-resolution, genome-wide mapping of SMAD2/3 complexes under physiological conditions. These models ...
PNAS published a clinical update in Research Highlights on 30 Mar 2026.
The item focuses on Versatile SMAD2 and SMAD3 epitope–tagged mouse models for genomic profiling of TGFβ signaling: Uncovering GDF9–SMAD2/3 targets.
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