Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificanceMultiple system atrophy (MSA) is a rapidly progressive synucleinopathy, yet the mechanisms linking α-synuclein pathology to neurodegeneration and the role of adaptive immunity in this process remain poorly understood. We used single-cell ...
PNAS published a clinical update in Research Highlights on 30 Mar 2026.
The item focuses on Cytotoxic T cell recognition of α-synuclein drives pathogenic immune responses in multiple system atrophy.
Review the original article for the full source wording and details.