Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificancePromoting endogenous cardiomyocyte proliferation is emerging as a promising strategy for cardiac repair. Here, we reveal thatRetsatactivates cardiomyocyte cell cycle reentry and promotes cardiac regeneration independently of its canonical ...
PNAS published a clinical update in Research Highlights on 31 Mar 2026.
The item focuses on Retinol saturase in the mitochondria antagonizes IDH2 and GLUD1 acetylation to mediate heart repair.
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