Convergence of external and internal stressors on a stress-responsive enhancer of the Sonic hedgehog gene to induce hair disorders

Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificanceIt is conceivable that stress impacts our health through perturbation of the intrinsic regulatory molecular pathways. Here, we used the fast-growing hair follicles as a model, and showed that various stressors suppress the expression ofSonic ...