Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificanceDeciphering the mechanisms underlying antitumor immunity is critical for improving the efficacy of cancer immunotherapy. In cancer cells, there are aberrantly accumulated double-stranded RNAs (dsRNAs) that can be recognized by RNA sensor ...
PNAS published a clinical update in Research Highlights on 31 Mar 2026.
The item focuses on WFDC21P is essential for G3BP1-mediated RIG-I activation and antitumor immunity in triple-negative breast cancer.
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