Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceFerroptosis, a regulated cell death program induced by phospholipid (PL) peroxidation, has been extensively studied in cancer cells as a therapeutic strategy; however, its characterization in primary T cells remains poorly understood. Here, ...
PNAS published a clinical update in Research Highlights on 24 Mar 2026.
The item focuses on The phospholipid profile of T cells shapes ACSL4 dependency and ferroptosis sensitivity of naive, effector, and memory T cells.
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