Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceWe report on the applicability of a CLIPS (chemical linkage of peptides onto scaffolds) chemistry–based strategy to miniaturize an anti-influenza hemagglutinin (HA) antibody into design of stable and functional bicyclic peptides by merging ...
PNAS published a clinical update in Research Highlights on 24 Mar 2026.
The item focuses on Small molecule–constrained paratope mimetic bicyclic peptides as potent inhibitors of group 1 and 2 influenza A virus hemagglutinins.
Review the original article for the full source wording and details.