Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceThe adipose tissue is a central hub of metabolic and endocrine regulation with a major impact on aging.
We identify the conserved miRNA-processing enzyme Dicer-1 (Dcr-1) as a crucial regulator of adipose tissue physiology and lifespan. Reduced ...
PNAS published a clinical update in Research Highlights on 24 Mar 2026.
The item focuses on Adipose Dicer-1 modulates systemic insulin signaling and longevity via a miR-8–Aop–Dilp6 axis.
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