Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceThe role of DIRAS2 in epilepsy remains unexplored. In this study, we demonstrate that DIRAS2 alleviates epileptic seizure susceptibility and activity and regulates the excitatory/inhibitory balance. Mechanistically, DIRAS2 suppresses ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceThe role of DIRAS2 in epilepsy remains unexplored. In this study, we demonstrate that DIRAS2 alleviates epileptic seizure susceptibility and activity and regulates the excitatory/inhibitory balance. Mechanistically, DIRAS2 suppresses ...