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Live · 18 articles · Rheumatology · Updated 11:00 pm
The application of **single-cell genomics** to immune-mediated arthritis has produced an extensive, rapidly expanding dataset that reveals diverse immune and stromal cell subsets in diseased joints. -...
The source article metadata (title, journal, and URL) was provided but the full article body was not included; detailed findings, methods, and conclusions were not reported in the source text. - The a...
Osteoarthritis (OA) is a chronic degenerative joint disease with limited disease-modifying treatments; identification of biomarkers could improve diagnosis and therapy. - The study integrated synovial...
This study investigated **phycocyanobilin**, a chromophore from Arthrospira platensis (Spirulina), for potential relevance to **systemic lupus erythematosus (SLE)** based on structural similarity to *...
**Tocilizumab** (TCZ) is a monoclonal antibody targeting the interleukin-6 receptor, utilized in rheumatoid arthritis (RA). - This study evaluated TCZ's real-world effectiveness and safety in **44 Mor...
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The FDA approved **Lisraya** (brepocitinib) tablets as the first FDA‑approved oral therapy indicated for adults with **dermatomyositis**, addressing a long‑standing unmet need for this rare autoimmune...
The study combined previously published **massively parallel reporter assay (MPRA)** results with human expression datasets to identify cells and target genes affected by JIA-associated SNPs. - MPRA-i...
This report presents the phase 1 portion of the COMPARE trial testing autologous fully human **CD19 CAR T cell** therapy, mivocabtagene autoleucel (**miv-cel**), in treatment-refractory, seropositive...
Juvenile systemic sclerosis (jSSc) is a rare autoimmune condition with skin fibrosis and multi-organ involvement; autologous stem cell transplantation (ASCT) is an emerging therapy for severe, refract...
The full article text and substantive content were not available in the provided source excerpt; only journal navigation and metadata were present. - The original article title indicates a focus on th...
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