Long COVID is an infection-associated chronic condition that occurs after SARS-CoV-2 infection and can lead to sometimes severe disability.1–3 In early 2024, long COVID had already affected 400 million people, with an estimated annual global economic impact of US$1 trillion.2 6 years into the COVID-19 pandemic, research into long COVID has progressed considerably, and evidence implicates several pathomechanisms, including aberrant immunity, persistent pathogens, endothelial dysfunction, and mitochondrial dysfunction.
The Lancet Infectious Diseases published a clinical update in Infectious Disease on 31 Mar 2026. The item focuses on The case for routine patient review in long COVID research. Open the detail page to review the full original feed content.