In people with fibrotic ILD and exertional hypoxaemia, ambulatory oxygen delivered using a portable concentrator did not provide benefits over ambulatory air for physical activity in daily life. Routine prescription of ambulatory oxygen using a portable oxygen concentrator for people with fibrotic ILD with isolated exertional hypoxaemia might not be indicated. These results reinforce the pressing need for innovation in portable oxygen devices to ensure effective oxygen delivery and acceptability to patients.
The Lancet Respiratory Medicine published a clinical update in Critical Care on 26 Feb 2026.
The item focuses on Ambulatory oxygen for treatment of exertional hypoxaemia in pulmonary fibrosis (PFOX): a multicentre, randomised, sham-controlled trial.
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