PNASPublic Health
Chromosome-specific drift under stabilizing selection generates polygenic barriers to sex chromosome turnover
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceSex-determining mechanisms show striking evolutionary contrasts across the tree of life. In some clades they change frequently, while in others they remain unchanged for millions of years. Here, I show that stabilizing selection on polygenic ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceSex-determining mechanisms show striking evolutionary contrasts across the tree of life. In some clades they change frequently, while in others they remain unchanged for millions of years. Here, I show that stabilizing selection on polygenic ...