PNASPublic Health
Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceFew reversible male contraceptives have advanced toward clinical translation, largely because the optimal biological stage for safe intervention remains undefined. Meiosis represents a natural checkpoint in sperm production where transient ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceFew reversible male contraceptives have advanced toward clinical translation, largely because the optimal biological stage for safe intervention remains undefined. Meiosis represents a natural checkpoint in sperm production where transient ...