PNASPublic Health
Deep learning–enabled scaffolding of spatial arrays of PfCSP epitopes
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceMalaria is a leading cause of disease in developing countries. Monoclonal antibody L9 has been shown to provide potent protection against malaria in humans. L9 binds to NPNV motifs within the circumsporozoite protein (CSP), with three L9 Fabs ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceMalaria is a leading cause of disease in developing countries. Monoclonal antibody L9 has been shown to provide potent protection against malaria in humans. L9 binds to NPNV motifs within the circumsporozoite protein (CSP), with three L9 Fabs ...