PNASPublic Health
Niche-dependent modular regulation of the stem cell transcriptome separates cell identity and potential
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceDedifferentiation is a mechanism by which differentiating cells revert back to stem cell identity to compensate for the loss of stem cells, allowing for long-term tissue homeostasis. It remains poorly understood how stem cells and progeny ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceDedifferentiation is a mechanism by which differentiating cells revert back to stem cell identity to compensate for the loss of stem cells, allowing for long-term tissue homeostasis. It remains poorly understood how stem cells and progeny ...