PNASPublic Health
Structural insights into measles virus RNA synthesis regulation and pan-paramyxoviral polymerase inhibition by ERDRP-0519
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceNonsegmented negative-sense RNA viruses (nsNSVs), including measles and Nipah viruses, pose major health threats yet lack effective antivirals. These pathogens rely on a large RNA-dependent RNA polymerase (RdRP) complex to replicate and ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceNonsegmented negative-sense RNA viruses (nsNSVs), including measles and Nipah viruses, pose major health threats yet lack effective antivirals. These pathogens rely on a large RNA-dependent RNA polymerase (RdRP) complex to replicate and ...