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Chaperone-mediated autophagy protects against retinal photoreceptor degeneration by modulating proteostasis of glucose metabolism enzymes
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 20, May 2026. SignificanceMaintenance of retinal proteostasis is essential for normal function, and its failure underlies common age-related degenerative retinal diseases. In this study, we show that chaperone-mediated autophagy (CMA), a selective form of autophagy ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 20, May 2026. SignificanceMaintenance of retinal proteostasis is essential for normal function, and its failure underlies common age-related degenerative retinal diseases. In this study, we show that chaperone-mediated autophagy (CMA), a selective form of autophagy ...