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Structural and dynamic basis of indirect apoptosis inhibition by Bcl-xL: A case study with Bid
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 20, May 2026. SignificanceProgrammed cell death, or apoptosis, is a fundamental process that eliminates damaged cells. However, cancer cells often evade this process by overexpressing antiapoptotic Bcl-2 family proteins, which neutralize their proapoptotic ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 20, May 2026. SignificanceProgrammed cell death, or apoptosis, is a fundamental process that eliminates damaged cells. However, cancer cells often evade this process by overexpressing antiapoptotic Bcl-2 family proteins, which neutralize their proapoptotic ...