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Munc13 serves as a molecular filter for SNARE sorting and assembly in active zone condensates
Summary
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceOur study reveals that the recruitment of Munc13-1 into RIM1/RIM-BP2 biomolecular condensates is not merely a localization event but a fundamental mechanism that confers transformative new functions. Within the condensate, Munc13-1 evolves ...
Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. SignificanceOur study reveals that the recruitment of Munc13-1 into RIM1/RIM-BP2 biomolecular condensates is not merely a localization event but a fundamental mechanism that confers transformative new functions. Within the condensate, Munc13-1 evolves ...