Objectives The study aimed to determine treatment outcome and factors affecting treatment outcomes among hospitalised patients with skin and soft tissue infections (SSTIs) at the University of Gondar Comprehensive Specialised Hospital (UOGCSH) in Ethiopia. Participants 423 patients from all age groups with clinically diagnosed SSTIs from 25 June to 25 December 2023 at the UOGCSH were included.
Outcome measures Primary treatment outcomes were early apparent clinical response within 48–72 hours and treatment failure after 72 hours of optimal antibiotic therapy. Secondary treatment outcomes included hospital length of stay (HLOS) and in-hospital mortality.
Multiple linear regression assessed factors influencing the HLOS, and multivariable logistic regression identified predictors of treatment failure. Results The average HLOS was 13.46±3.01 days.
Of the patients, 39.3% had an early clinical response within 48–72 hours, whereas 34.4% had treatment failure. At 0.7%, the in-hospital death rate was modest.
BMJ Open published a clinical update in Research Highlights on 13 May 2026.
The item focuses on Determinants of treatment outcomes among hospitalised patients with skin and soft tissue infections: a prospective observational study.
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