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Molecular analyses of African swine fever (ASF) outbreaks in northern and central Vietnam during 2023–2024 revealed a rapid expansion (14.1%–42.2%) of recombinant ASF virus genotypes I and II. Increased prevalence and resistance to commercial ASF vaccines underscore the urgent need for better ASF control and an updated vaccine in Vietnam.
African swine fever (ASF) is a highly contagious viral disease affecting domestic and wild pigs; mortality rates reach up to 100% ( 1 ). The causative agent, ASF virus (ASFV), is a large double-stranded DNA virus in the Asfarviridae family.
ASFV strains have been classified into 24 genotypes, of which only genotypes I and II have spread beyond Africa ( 2 ). In Asia, ASFV genotype II was first detected in China in 2018 ( 3 ) and in Vietnam in early 2019 ( 4 ).
CDC Emerging Infectious Diseases Journal published a clinical update in Infectious Disease on 10 Apr 2026.
The item focuses on Rapid Spread of Recombinant African Swine Fever Virus Genotypes I and II, Vietnam, 2023–2024.
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