Ultrasound Guided EXORA Block in Umbilical Hernia Surgery

This clinical trial evaluates whether an ultrasound-guided block of the external oblique and rectus abdominis plane (EXORA) can influence neuroendocrine stress responses and postoperative pain in adults undergoing umbilical hernia repair. The intervention uses regional anesthesia targeting the abdominal wall planes with ultrasound guidance, aiming to modulate the physiological stress associated with surgery and the patient’s analgesic needs. Key design elements stated are prospective and randomized, with an intervention focus rather than observation. The primary purpose is treatment, addressing whether EXORA provides benefit regarding neuroendocrine response and analgesia in the specified surgical population. The study plans to enroll approximately 100 participants and is currently in the recruiting stage, with an estimated completion date in September 2026. Uncertainty and limitations: The provided content does not include details on outcome measures, specific neuroendocrine markers, exact analgesic protocols, anesthesia techniques, blinding, randomization methods, or safety endpoints. Consequently, interpretation of potential efficacy or safety cannot be ascertained from the information given.