BackgroundInflammatory bowel disease (IBD) is a chronic condition characterized by recurrent inflammatory episodes in the gastrointestinal tract. Conventional therapies, including biologics, corticosteroids, and immunosuppressive drugs, can effectively alleviate disease activity.
However, their utility is often limited by adverse effects. Vitamin D plays a role in modulating immune function, intestinal barrier integrity, and the gut microbiota.
It has emerged as a promising adjunctive therapy for IBD.ObjectiveTo map the research landscape of vitamin D in IBD using bibliometric analysis, focusing on knowledge evolution, core themes, and emerging trends.MethodsPublications from 2006 to 2025 were collected by searching the Web of Science Core Collection (WoSCC) and Scopus databases. After removing duplicates, 2,659 articles and reviews were obtained for analysis.
Networks were constructed using CiteSpace, VOSviewer, R, and Python. PubMed clinical trials were included for complementary analysis, and BERTopic was applied to identify latent topics and their temporal dynamics.ResultsA total of 2,659 publications spanning 970 journals were identified, with a steady increase in output.
The USA was the leading contributor and also demonstrated strong international collaboration. Ananthakrishnan Ashwin N.
Frontiers in Immunology published a clinical update in Infectious Disease on 29 May 2026.
The item focuses on From nutritional intervention to immune modulation: a multi-database bibliometric and topic modeling study of vitamin D in inflammatory bowel disease.
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