The PubMed entry reports a manuscript titled "Genomic insights into an optrA-carrying plasmid associated with linezolid resistance in clinical Enterococcus faecalis isolates, Argentina." The article is listed in European Journal of Clinical Microbiology and Infectious Diseases, noted as online ahead of print in 2026 (DOI 10.1007/s10096-026-05657-4) and indexed with PMID 42678601.
The title indicates the study's focus on genomic characterization of a plasmid harboring optrA that is associated with linezolid resistance in clinical Enterococcus faecalis isolates from Argentina. Beyond the bibliographic metadata and author affiliations, the PubMed record provided does not include the abstract text or the detailed manuscript content.
The author list includes Celia María Schell and multiple collaborators spanning institutions in Argentina, Italy, China, and Germany. Key affiliations reported on the PubMed page include:
The PubMed record lists Andrea Brenciani with an email address in the affiliations; this may serve as a corresponding-author contact, as indicated on the page.
According to the title, the objective of the reported work was to provide genomic insights into a plasmid carrying optrA that is associated with linezolid resistance in clinical Enterococcus faecalis isolates from Argentina. The PubMed entry confirms the geographic and microbiological scope (Argentina; clinical E. faecalis) and that the focus is a plasmid-borne resistance determinant.
The entry denotes a genomic approach to characterizing an optrA-carrying plasmid linked to linezolid resistance, implying analyses at the DNA sequence and plasmid-structure level. However, the PubMed summary available here does not include the abstract or the manuscript body; therefore, the specific genomic methods used (for example, sequencing platforms, assembly approaches, or comparative analyses), the plasmid architecture, gene contexts, or sequence accession numbers are not reported in this source record.
The PubMed page supplied does not include the article abstract or detailed sections (methods, results, discussion). As a result, the following specific information is not available from this source alone: number and origin of clinical isolates, antimicrobial susceptibility data, genomic findings (plasmid size, gene content, mobile elements), phylogenetic analyses, evidence for plasmid transferability, or the authors' conclusions and recommendations.
To obtain those details, readers should access the full text through the journal (Eur J Clin Microbiol Infect Dis) or a full-text database using the DOI 10.1007/s10096-026-05657-4 or the PMID 42678601.
The PubMed metadata and the article title identify a clinically relevant subject: a plasmid-borne optrA determinant associated with linezolid resistance in clinical Enterococcus faecalis. The title signals that genomic data underpin the reported observations, which may be relevant to surveillance of linezolid resistance and plasmid-mediated dissemination. The PubMed record itself does not provide the authors' discussion of clinical implications or detailed evidence; those elements must be consulted in the full manuscript.
For accurate citation, data extraction, and application to clinical practice or research, obtain and review the full article text. The PubMed record provides complete author and affiliation listings but does not substitute for the manuscript content needed to evaluate methods, results, and conclusions.
Notes: The content above is limited to the information present in the PubMed record provided. Specific experimental details, results, sequence data, and authors' interpretations were not reported in that source and therefore are not included here.