Journal of the American Heart Association, Volume 15, Issue 6 , March 17, 2026. BackgroundThere is no universal agreement on the diagnostic criteria for cardiac sarcoidosis (CS).
In 2024, the American Heart Association (AHA) introduced a new diagnostic scheme featuring a quaternary likelihood stratification for CS instead of dichotomy. Its clinical implications are unknown.MethodsWe analyzed 252 patients with CS and proven histology (mean age, 49 years; 61% women).
Following the AHA diagnostic stratification, CS was retrospectively considered definite given sarcoid granulomas on myocardial biopsy (n=109), highly probable with both clinical and cardiac imaging findings being CS consistent (n=93), and probable with either clinical or imaging findings alone being CS consistent (n=50).
Journal of the American Heart Association published a clinical update in Cardiology on 13 Mar 2026.
The item focuses on Implications of the 2024 American Heart Association Classification of Cardiac Sarcoidosis: Characteristics and Outcome of Patients Across the Continuum of Diagnostic Likelihood.
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