Preeclampsia and Eclampsia: A Complex Interplay Between Prepregnancy Obesity, Race, and Ethnicity

15 Jun 20264 min read0 viewsJournal Feed

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Journal of the American Heart Association, Volume 15, Issue 12 , June 16, 2026. Background. Preeclampsia and eclampsia (PE/E) are major contributors to maternal morbidity and mortality in the United States, disproportionately affecting Black, Hispanic, and American Indian/Alaska Native individuals.
Prepregnancy obesity is a well‐established risk factor, but the variation of its association with PE/E by race and ethnicity, particularly among Asian/Pacific Islander (PI) and Hispanic subpopulations, remains unclear. Methods. This population‐based cohort study included 311 497 pregnancies at Kaiser Permanente Northern California from 2011 to 2020.
We used Poisson regression to estimate adjusted relative risks (aRRs) for PE/E by prepregnancy body mass index (BMI), stratified by race and ethnicity and adjusted for sociodemographic, clinical, and neighborhood‐level factors. Results. The overall PE/E prevalence was 4.6%, highest among Black (6.8%) and lowest among Asian/PI (4.2%) and White (4.1%) individuals.
PE/E prevalence increased with higher BMI across all groups, but the strength of the association varied.

Journal of the American Heart Association published a clinical update in Cardiology on 15 Jun 2026.

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Journal of the American Heart Association