Journal of the American Heart Association, Volume 15, Issue 11 , June 2, 2026. BackgroundSignificant tricuspid regurgitation (TR) leads to right ventricular dysfunction and associated comorbidities.
As the receiving chamber for regurgitant volume, the right atrium undergoes significant mechanical remodeling. This study investigated whether right atrial reservoir strain (RArS), a key marker of atrial mechanics, serves as a prognostic indicator for mortality in patients with moderate‐to‐severe TR.MethodsClinical, laboratory, and echocardiographic data from 289 consecutive patients with TR (grade ≥+3) were analyzed.
RArS was evaluated by 2‐dimensional speckle‐tracking echocardiography using semiautomated software (TOMTEC; Philips). The cohort was divided into 2 groups by RArS above or below the median value.ResultsA total of 239 patients (mean age 82 years, 55% women) were included in the final study.
Median RArS was 11.7%. Compared with patients with higher RArS, patients with RArS below median had a higher rate of atrial fibrillation and worse right ventricular function.
Lower RArS was also associated with wider inferior vena cava diameter, abnormal cholestatic liver enzymes, and a higher rate of diuretic use.
Journal of the American Heart Association published a clinical update in Cardiology on 25 May 2026.
The item focuses on Prognostic Value of Right Atrial Strain in Patients With Moderate‐to‐Severe Tricuspid Regurgitation.
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