Overweight/obesity, diabetes, and hypertension are major risk factors for cardiovascular and kidney disease. They are all part of the recently coined cardiovascular-kidney-metabolic syndrome.1 Adipose tissue crosstalk with the vasculature plays an important role in maintaining vascular structure and function and thereby controlling blood pressure.2 It is noteworthy that the type of adipose tissue, more than the total amount, is a particularly critical factor in blood pressure regulation. Whereas excess white fat, especially visceral adiposity, is associated with increased blood pressure and risk of cardiovascular disease, brown fat produces heat and is associated with decreased cardiovascular risk, even in the presence of obesity.
Kidney International published a clinical update in Research Highlights on 16 Apr 2026. The item focuses on Perivascular fat, hypertension, and cardiovascular disease. Open the detail page to review the full original feed content.