A 73-year-old man was admitted with a 1-month history of macroscopic hematuria and progressive decline in his general condition. His medical history was significant for κ light-chain multiple myeloma with isolated bone involvement, diagnosed 10 years earlier and treated with lenalidomide-dexamethasone.
Laboratory investigations revealed acute kidney injury (serum creatinine level 559.6 μmol/l; baseline level 79.5 μmol/l), a hemoglobin level of 10.8 g/dl, and a serum calcium level of 2.5 mmol/l. The κ/λ free light-chain ratio was 68, with κ free light chains measured at 962 mg/l.
Kidney International published a clinical update in Research Highlights on 13 Mar 2026.
The item focuses on Extramedullary plasmacytoma with renal involvement.
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