Nature Immunology, Published online: 13 April 2026; doi:10.1038/s41590-026-02493-8 Metabolic stress is associated with impaired immunity, yet underlying mechanisms remain unclear. Description of a xanthine-dependent antioxidant program that shields CD8+ T cells from ferroptosis reveals a metabolically actionable axis that control anti-tumor responses.
Nature Immunology published a clinical update in Infectious Disease on 13 Apr 2026.
The item focuses on Diet-induced metabolic memory shapes CD8 + T cell ferroptosis susceptibility.
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