In this issue of Nature Reviews Neurology , we launch a Collection that explores the multisystemic nature of neurological disease and highlights the importance of collaboration between neurology and other clinical specialties. The remit of Nature Reviews Neurology is to cover conditions characterized by impaired function of the central and peripheral nervous systems.
However, the nervous system does not operate in isolation, and neurological diseases often affect multiple organs and systems in the body. Conversely, many diseases that are traditionally considered to be non-neurological have neurological symptoms and sequelae.
In the April 2026 issue of Nature Reviews Neurology , we launch a new Collection that highlights the multisystemic nature of such diseases and the importance of collaboration between neurology and other clinical disciplines. The issue includes two Reviews that were specially commissioned for the Collection.
The first, by Matthias Endres and colleagues, explores the bidirectional relationship between the heart and the brain , showing how injury to or dysfunction of one of these organs can adversely affect the other.
Nature Reviews Neurology published a clinical update in Neurology on 02 Apr 2026.
The item focuses on Multisystemic aspects of neurology.
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