Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceAlthough cells continuously integrate diverse environmental cues, the mechanisms by which aging reprograms mechanical and biochemical signaling remain poorly understood. We demonstrate that aged fibroblasts lose the capacity to mount ...
PNAS published a clinical update in Research Highlights on 26 Mar 2026.
The item focuses on Chromatin accessibility regulates age-dependent nuclear mechanotransduction.
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