Proceedings of the National Academy of Sciences, Volume 123, Issue 13, March 2026. SignificanceApolipoprotein L-1 (APOL1) provides primates immunity to trypanosome infection.
Other animals do not express the protein and are thus susceptible to trypanosomiasis, with cattle in particular routinely succumbing to infection. Fresard et al., ...
PNAS published a clinical update in Research Highlights on 27 Mar 2026.
The item focuses on Germline-targeted baboon apolipoprotein L-1 protects mice against African trypanosomes.
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