An erratum published in Blood Purif (online ahead of print, 2026 Aug 4) addresses an error in Figure 1 of the consensus article titled "Extracorporeal Blood Purification with the oXiris® Filter for Patients with Sepsis and Hyperinflammatory Conditions: The Asia-Pacific oXiris Expert Meeting 2024 Consensus Statements" (Zhang et al., Blood Purif. 2025;54(11):621-638; DOI 10.1159/000548214). The erratum itself is indexed (PMID 42550780; DOI 10.1159/000552410) and corrects wording in the treatment algorithm figure used to guide CRRT and oXiris filter use in sepsis, septic shock, severe COVID-19, and other hyperinflammatory states.
The error occurred in the "Evaluate treatment success/failure" section of Figure 1, specifically within the column labeled "Failure." The figure originally stated: "Improvement in hemodynamic parameters/dependence on vasopressors after 72 hours." The erratum clarifies that the word omitted during figure preparation was "No." The correct failure criterion should read: "No improvement in hemodynamic parameters/dependence on vasopressors after 72 hours."
The erratum states this omission was introduced during preparation of the figure and that the corrected wording has been verified by cross-referencing the figure with the main text and table in the original article.
Figure 1 of the original consensus article presents a treatment algorithm for oXiris filter use in patients requiring CRRT with sepsis/septic shock, severe COVID-19, or other hyperinflammatory conditions. The figure included a legend listing multiple abbreviations and clinical measures used within the algorithm, such as AKI, APACHE, CRP, CVVH, CVVHD, CVVHDF, EAA, ECMO, HIT, SOFA, KDIGO, PCT, IL, PaO2/FiO2, SCUF, and TNF. The algorithm is intended to guide assessment of treatment success versus failure and decisions around continuation or cessation of oXiris-assisted extracorporeal blood purification.
The erratum reports that the corrected wording in Figure 1 matches the language used elsewhere in the original publication. Specifically, Statement 5.1 in the main text (page 630) and Table 1 (page 625) of the original consensus article both consistently and correctly state the treatment futility criterion as: "No improvement in hemodynamic parameters/dependence on vasopressors after 72 hours." The erratum thereby confirms that the omission in Figure 1 was an isolated preparation error in the figure and not a change in the authors' intended clinical recommendation.
This formal correction is published as an erratum in Blood Purif. The erratum entry lists no authors, provides the PubMed identifier (PMID 42550780) and DOI (10.1159/000552410), and indicates the item is an official published erratum. The erratum reproduces the corrected Figure 1 and records that the correction was made to align the figure with existing statements in the original paper. The original consensus article citation and author list are provided within the erratum for reference (Zhang L, Srisawat N, Lee CC, Lee DH, Lee K, Liu Z, Mohamad Nor FS, Mustafar RB, Peerapornratana S, Pham HM, Sewa SDW, Tang GKY, Yeh YC, Zhu M, Yao Q, Wang M, Bellomo R; Blood Purif. 2025;54(11):621-638; PMID 40929000).
The correction clarifies the treatment futility threshold in the figure: lack of hemodynamic improvement or persistent dependence on vasopressors at 72 hours is a criterion for labeling the intervention as a failure. According to the erratum, this wording is the intended and previously stated criterion in the main text and table of the consensus document. The erratum does not report other changes to recommendations, statements, or tables in the original publication.
Clinicians referring to the consensus algorithm should use the corrected Figure 1 language when assessing ongoing oXiris-supported extracorporeal blood purification and make clinical decisions consistent with Statement 5.1 and Table 1 of the original article.
All details in this erratum are taken directly from the erratum notice as published and indexed on PubMed. The erratum attributes the omission to figure preparation and confirms consistency with the original article's main text and table. No additional data, altered recommendations beyond the corrected sentence, or further errata were reported in this notice.