Frontline healthcare workers (HCWs) are among the professions most affected by epidemic and pandemic respiratory pathogens. During the COVID-19 pandemic, HCWs faced increased occupational exposure to SARS-CoV-2. This investigation was designed to determine the seroprevalence of SARS-CoV-2 antibodies among frontline HCWs in selected health facilities in Nigeria during the latter half of 2022.
The study used a cross-sectional design conducted from August 2022 through December 2022 (epidemiologic weeks 31–51). Data were collected at seven healthcare facilities located in three Nigerian states. The work was published as an eCollection in PLoS One in 2026.
A total of 1,247 HCWs were randomly selected and enrolled in the study. These participants represented frontline clinical staff at the participating facilities. The provided source excerpt does not present additional demographic or occupational breakdowns (for example, age, sex, profession, or years of clinical experience).
The abstract indicates the study had two parts and explicitly states one component involved assessment of knowledge and attitudes; however, the supplied text is truncated and does not include a complete description of the second component or full detail about data collection procedures. The excerpt does not report the specific serologic assays or laboratory methods used to detect antibodies, nor does it indicate whether antibody targets (e.g., anti-nucleocapsid versus anti-spike) or thresholds for seropositivity were predefined.
The article title and the abstract header convey that there was a high prevalence of SARS-CoV-2 antibodies among frontline HCWs in the sampled Nigerian facilities during the study period. The supplied excerpt, however, does not include numeric seroprevalence estimates, confidence intervals, subgroup analyses, comparisons by facility or state, or statistical tests. Because those quantitative results and analytic details are not present in the provided text, they are not reported here.
The work lists numerous contributing authors and participating institutions. Affiliations reported in the supplied excerpt include:
The author group is listed under the SECURE Nigeria Project Team and includes multiple named investigators; full author-level contributions and order are noted in the original citation but are not expanded in this excerpt.
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The provided source excerpt is incomplete. Specific limitations arising from the truncation of the abstract and absence of the full text include:
When the full article is available, readers should consult it for the complete methodology, detailed results, subgroup analyses, statistical findings, discussion of implications, and declared conflicts of interest. The current summary restricts itself to information explicitly present in the supplied PubMed/NCBI excerpt and notes where details were not reported in that excerpt.