The PubMed record describes a 2026 article titled “Multifunctional anti-CD33 antibody- and polydopamine-coated curcumin-indocyanine green nanoparticles for in vitro cytotoxic effects against leukemia cells.” The title indicates the authors developed a nanoparticle formulation combining an anti-CD33 antibody and a polydopamine surface coating with curcumin and indocyanine green (ICG) as payloads, and that the investigation targeted in vitro cytotoxic effects against leukemia cells.
The PubMed entry provides bibliographic and author metadata but does not include the abstract or experimental results in the content supplied here. Therefore the record confirms the study focus and design elements only at the level conveyed by the article title and metadata.
Authors listed on the PubMed page include Pinyadapat Aroonthongsawat, Xue Feng, Yuxuan Ji, Yuxiang Xue, Nurbanu Ozgultekin, Hongdi Wang, Mengguang Ye, Norbert Radacsi, Primana Punnakitikashem, Xianfeng Chen, and Yaneenart Suwanwong. Multiple institutional affiliations are reported across the entry.
Affiliations shown in the record include the Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University (Bangkok, Thailand); School of Engineering, Institute for Bioengineering, University of Edinburgh (United Kingdom); Institute for Materials and Processes and Centre for Cardiovascular Science at the University of Edinburgh; Department of Biochemistry, Faculty of Medicine, Siriraj Hospital and the Siriraj Center of Research Excellence in Theranostic Nanomedicine, Mahidol University (Bangkok, Thailand); and the Center of Excellence for Biosensors and Bioengineering (CEBB), Chulalongkorn University. Two electronic contact addresses are provided for Xianfeng Chen and Yaneenart Suwanwong in the PubMed entry.
The article is published in International Journal of Pharmaceutics (Int J Pharm). The PubMed citation lists an electronic publication date of 2026 Jul 27 and journal pagination or identifier 2026 Sep 5:702:127202. The DOI is 10.1016/j.ijpharm.2026.127202 and the PubMed identifier (PMID) is 42508510. The entry is marked as a free article and contains a link to Elsevier Science full-text options.
From the title alone, the formulation described combines several elements:
Targeting moiety: an anti-CD33 antibody, which by implication targets CD33-expressing cells (CD33 is commonly expressed on myeloid leukemia cells). The PubMed record does not provide experimental confirmation of target expression or targeting efficacy.
Surface chemistry: a polydopamine-coated outer layer, as stated in the title. The record does not report coating characterization, stability, or rationale beyond the title.
Payloads: inclusion of curcumin and indocyanine green (ICG) within the nanoparticles, per the title. No encapsulation efficiency, release kinetics, or photophysical properties are reported in the PubMed summary.
Intended evaluation: assessment of in vitro cytotoxic effects against leukemia cells. The PubMed entry does not present which leukemia cell lines were used, the assay formats, or any quantitative cytotoxicity data.
The title specifies an in vitro cytotoxicity evaluation against leukemia cells, implying the study conducted cell-based assays to assess nanoparticle-induced cell death or growth inhibition. The PubMed metadata available here does not contain the abstract or methods, so the specific assays (for example, viability assays, apoptosis markers, dose–response curves), exposure conditions, controls, or comparative arms are not described.
The PubMed page content provided in this source consists primarily of bibliographic metadata, author lists, affiliations, DOI, PMID and links. The following key items are not included in the displayed content and therefore are not available from this source alone:
Because these items are absent from the PubMed summary presented here, any interpretation of efficacy, safety, or mechanism would require consulting the full text.
The PubMed entry includes a link to Elsevier Science full-text options. To obtain complete experimental details and results, readers should follow the publisher link provided on the PubMed page, access the article via institutional or personal subscription, or check whether the article is available freely through the journal’s website or an open-access repository. The PubMed record itself does not provide the study content beyond metadata and title information.
This PubMed record documents a 2026 Int J Pharm article about multifunctional nanoparticles combining an anti-CD33 antibody and polydopamine coating with curcumin‑ICG payloads, aimed at assessing in vitro cytotoxic effects against leukemia cells. The record supplies full citation details, authorship and affiliations, but the abstract, methods, and results are not present in the provided source content. For experimental findings and clinical or preclinical interpretation, consult the article’s full text via the publisher link or other authorized access routes.