This PubMed entry describes a single-center retrospective clinical study investigating the efficacy and safety of spatially fractionated radiation therapy in patients with advanced/recurrent metastatic malignant tumors. The title specifies the clinical focus (advanced or recurrent metastatic disease) and the intervention (spatially fractionated radiation therapy). The study design is reported as retrospective and single-center.
The PubMed record presented here contains bibliographic metadata but does not include the study abstract or numeric results within the visible summary. Therefore, while the study aim and design are clear from the title, specific details on patient selection, treatment parameters, outcomes, and adverse events are not available in the provided source.
The article is published in Zhonghua Zhong Liu Za Zhi with citation details: 2026 Sep 23;48(9):1166-1174. The PubMed identifier (PMID) is 42764222 and the DOI is 10.3760/cma.j.cn112152-20250717-00344.
The work is authored by L N Chen and multiple coauthors (Z T Dai; W J Zhang; L L Feng; J Q Lei; X Y Xiang; S M Jia; Y J Jia; X Y Su; Y T Tan; T D Lei; N Hu; E Z Quan; Q Xiao; J Jin). Affiliations provided indicate the Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, China. One author (J Jin) has an additional affiliation with the Beijing campus of the same institutional system.
The article is noted to be in Chinese; a full-text link via the Chinese Medical Association Publishing House is listed on the PubMed record.
The only study-design elements explicitly stated in the PubMed metadata are:
Other essential methodological details—such as sample size, tumor types included, inclusion and exclusion criteria, radiation planning parameters, device or delivery technique, dose and fractionation schemes, concurrent systemic therapies, outcome definitions (response criteria, local control, symptom relief, survival endpoints), follow-up duration, and statistical analysis methods—are not presented in the PubMed summary displayed.
The PubMed record includes a link labeled Chinese Medical Association Publishing House Ltd. for full-text access and indicates the article is written in Chinese. To review the study methodology and outcomes, readers should retrieve the full-text manuscript from the publisher link or institutional sources that provide access to Zhonghua Zhong Liu Za Zhi content.
The PubMed entry shown does not include the study abstract or results. Therefore, the following items were not reported in the source content provided:
Because these data are not present in the PubMed summary, no conclusions about the efficacy or safety profile of the intervention can be drawn from this source alone.
This PubMed record functions primarily as bibliographic metadata rather than a full scientific summary. The absence of abstracted methods and results in the displayed record limits the ability to evaluate the study’s internal validity, generalizability, and clinical implications.
Clinicians, guideline developers, and researchers should not attempt to incorporate findings from this study into practice or evidence syntheses based solely on the PubMed listing. Instead, the complete full-text article should be retrieved to assess:
The PubMed entry provides the DOI (10.3760/cma.j.cn112152-20250717-00344) and a link to the Chinese Medical Association Publishing House for full-text access. The article is in Chinese; non-Chinese readers may require translation services or an English abstract if one is made available elsewhere.
For a complete and reliable appraisal, retrieve and review the full-text manuscript. The full text will be necessary to extract numerical results, define the intervention precisely, and determine whether study findings are robust and applicable to specific patient populations.
Note: All factual statements in this summary are drawn from the PubMed metadata presented. The PubMed summary did not include the abstract or numerical results; therefore, no outcomes, statistics, or clinical recommendations are reported here because they were not present in the source material.